Breast cancer
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- (rev. 28)
- Hyungyong Kim
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Structured data
- Alternate Name
- 유방암
- URL
- http://en.wikipedia.org/wiki/Breast_cancer
Molecular classification of breast cancer (based on Hormonal receptors, Estrogen receptor, Progesterone receptor, HER2)
- Luminal A
- Luminal B
- HER-2 Enriched
- Basal-like
- Normal-like
- Claudin-low
ER+ luminal tumors has better prognosis by treatment with endocrine therapies including Aromatase inhibitors, or direct ER antagonists such as Tamoxifen and Fulvestrant.
BRCA1/BRCA2의 유전변이(germline variation)이 basal-like와 밀접하게 관련되어 있다.
Table of Contents
애니메이션 동영상 #
Breast tissue and stem cell
Breast cancer
관련링크 #
기사 #
- 유전성 유방·난소암 맞춤치료 시대 열린다 - 유전성유방암 변이 유전자 위치에 따라 유방·난소암 위험성 달라져 한국인 유전성유방암 연구회 참여, BRCA 보인자 3만명 분석결과 JAMA 발표
- Researchers use RNA-Seq to show that lincRNAs can also contribute to HER2+ breast cancers RNA-Seq Blog
논문 #
- Recurrent and functional regulatory mutations in breast cancer Nature : 360 사례 deep sequencing으로 FOXA1, RMRP, NEAT1의 non-coding 영역 프로모터에 유의한 변이 확인
- Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer : 유방암 유전체와 전사체에서의 somatic variance 차이 분석
- 유전체 의학 시대를 맞이한 유전성 유방암-난소암 증후군 유전 검사의 임상적 함의: 임상의사가 바라본 전망 Journal of Breast Disease
- The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes Nature Communications
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences Nature : 560 유방암 전장유전체(WGS) 분석
- 유방암에서 맞춤치료의 현황 Korean Journal of Clinical Oncology
- Comprehensive molecular portraits of human breast tumours Nature : 유방암 분자 병리에 대한 전반적인 이해를 위해 CNV, Exome sequencing, DNA methylation study, mRNA microarray, miRNA sequencing, reverse-phase protein array를 수행하고 분자적 메카니즘을 규명
관련 제품 #
관련 글 #
- Breast Cancer Awareness Month in every October 이수현
- 유방암 유전자 발견 20주년에 부쳐 강석기 : 젖가슴과 성선택은 진화적으로 관계가 없다는 얘기가 나오는데, 예쁜 가슴을 선호하는 남자의 성적 본능을 생각해보면 꼭 그렇지만은 않은 듯 하다.
Incoming Links #
[Medical Scholarly Articles] About (MedicalScholarlyArticle 0) #
- Comprehensive molecular portraits of human breast tumours
- DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression
- Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
- JARID1B is a luminal lineage-driving oncogene in breast cancer
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences
- MEL-18 loss mediates estrogen receptor–α downregulation and hormone independence
- Mutational processes molding the genomes of 21 breast cancers
- The life history of 21 breast cancers
- The topography of mutational processes in breast cancer genomes
Related Drug Classes (DrugClass 1) #
Related Datasets (Dataset 2) #
Related Books (Book 3) #
Related Drugs (Drug 4) #
Related Products (Product 5) #
Related Articles (Article 6) #
- BAP1
- BRCA1
- BRCA2
- BT-474
- Bone metastasis
- Breast cancer epigenetics: from DNA methylation to microRNAs
- CDH1
- CDK12
- COPS5
- Cancer epigenetics
- ChIP-seq
- Companion diagnostic
- Cytokeratin
- Drug discovery
- HMEC
- MCF-7
- MYC
- PAM50
- PI3K
- Receptor tyrosine kinase
- TLK2
- Triple-negative breast cancer
- 개인유전체 검사 결과를 설명하는 방법
- 암 맞춤의학과 생물정보학
Related Education Events (EducationEvent 7) #
[Datasets] About (Dataset 8) #
[Web Pages] About (WebPage 9) #
Related Medical Conditions (MedicalCondition 10) #
Related Medical Scholarly Articles (MedicalScholarlyArticle 11) #
- Breast cancer epigenetics: from DNA methylation to microRNAs
- Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers
- Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
- Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
- Methods of integrating data to uncover genotype–phenotype interactions
- Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection
- Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer
- Sequence analysis of mutations and translocations across breast cancer subtypes
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
[Articles] About (Article 12) #
Related Web Applications (WebApplication 13) #
Suggested Pages #
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- 0.032 Induced pluripotent stem cell
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