Estrogen receptors (ER) are a group of proteins found inside cells. They are receptors that are activated by the hormone Estrogen (17β-estradiol). (http://en.wikipedia.org/wiki/Estrogen_receptor)

Once activated by estrogen, the ER is able to translocate into the nucleus and bind to DNA to regulate the activity of different genes.

There are two different forms

• ESR1 - α
• ESR2 - β

Dimer를 형성함. ERα (αα) or ERβ (ββ) homodimers or ERαβ (αβ) heterodimers

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