Tamoxifen is an antagonist of the Estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen.

Tamoxifen is the usual endocrine (anti-estrogen) therapy for ER+ Breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

관련링크

• 20년간 유방암 발생률 평균 30% 감소시킨 타목시펜 2014-12-18

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