Aromatase inhibitors (AIs) are a class of drugs used in the treatment of Breast cancer and Ovarian cancer in postmenopausal women and gynecomastia in men.

It works by inhibiting the action of the enzyme Aromatase, which converts Androgen into Estrogen by a process called aromatization.

Members

• Non-selective
  • Aminoglutethimide
  • Testolactone (Teslac)
• Selective
  • Anastrozole (Arimidex)
  • Letrozole (Femara)
  • Exemestane (Aromasin)
  • Vorozole (Rivizor)
  • Formestane (Lentaron)
  • Fadrozole (Afema)

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