BRCA2 is a human Tumor suppressor gene (specifically, a caretaker gene), found in all humans; its protein, also called by the synonym Breast cancer type 2 susceptibility protein, is responsible for DNA repair. (http://en.wikipedia.org/wiki/BRCA2)
Michael Stratton이 년 발견함. 이를 기념하여, Addenbrooke's Hospital 부근 cycle and foot path를 만듬
Table of Contents
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- DNA repair
- Homologous recombination
- Homologous recombination deficiency
- Mutational signature
- Synthetic lethality
- Triple-negative breast cancer
- 암 맞춤의학과 생물정보학
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Related Medical Scholarly Articles (MedicalScholarlyArticle 6) #
- Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches
- Mechanisms underlying mutational signatures in human cancers
Suggested Pages #
- 0.099 HMEC
- 0.096 CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer
- 0.090 BRCA1
- 0.070 Nucleotide excision repair
- 0.065 Non-homologous end joining
- 0.046 BCIP
- 0.045 BT-474
- 0.031 CDK12
- 0.025 ERCC1
- 0.025 Copy-number variation
- More suggestions...