Homologous recombination deficiency (HRD). An HRD test is being applied to patient samples to identify BRCA1/BRCA2 mutated tumors, provide a categorical determination of tumor HRD, and determine an enrichment strategy for patients with tumors that are sensitive to Niraparib treatment.
Suggested Pages #
- 0.025 Mutational signature
- 0.025 February 13
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- 0.025 Addenbrooke's Hospital
- 0.025 Tumor suppressor gene
- 0.013 Two-hit hypothesis
- 0.013 Cancer genomics
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