Myc (c-Myc) is a regulator gene that codes for a Transcription factor. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in Cell cycle progression, Apoptosis and Cellular transformation. (http://en.wikipedia.org/wiki/Myc)
Hallmarks of Cancer
- MYC activates the expression of many genes that are involved in cell growth.
- MYC upregulates expression of Telomerase
- MYC is one of a handful of Transcription factors that can act together to reprogram somatic cells into pluripotent Stem cells.
- Through MYC upregulation,
It's deregulation (Oncogene effect) by
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