PARP inhibitor
#
Find similar titles
- (rev. 3)
- Hyungyong Kim
Structured data
PARP inhibitors are a group of pharmacological inhibitors of the enzyme poly ADP ribose polymerase (PARP)
Homologous recombination에 관여하는 PARP를 저해함으로 DNA repair를 못해서 Cancer cell이 사망하게 된다. 주로 BRCA1/BRCA2 결함 환자에게 적용한다.
치료제들
Incoming Links #
Related Articles (Article 0) #
Related Medical Scholarly Articles (MedicalScholarlyArticle 1) #
- CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer
- Triple-negative breast cancer: an unmet medical need
Suggested Pages #
- 0.236 Base excision repair
- 0.083 Copy-number variation
- 0.056 Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response
- 0.035 BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
- 0.025 Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality
- 0.025 MLH1
- 0.025 Hemangioma
- 0.025 Lipoma
- 0.025 Cell-free tumor DNA
- 0.025 Poly ADP ribose polymerase
- More suggestions...