PARP inhibitor
#
Find similar titles
- (rev. 3)
- Hyungyong Kim
Structured data
PARP inhibitors are a group of pharmacological inhibitors of the enzyme poly ADP ribose polymerase (PARP)
Homologous recombination에 관여하는 PARP를 저해함으로 DNA repair를 못해서 Cancer cell이 사망하게 된다. 주로 BRCA1/BRCA2 결함 환자에게 적용한다.
치료제들
Incoming Links #
Related Medical Scholarly Articles (MedicalScholarlyArticle 0) #
- CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer
- Triple-negative breast cancer: an unmet medical need
Related Articles (Article 1) #
Suggested Pages #
- 0.195 Base excision repair
- 0.185 Ageing
- 0.062 Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality
- 0.025 Hemangiosarcoma
- 0.025 XRCC4
- 0.025 Breast cancer
- 0.025 PMS1
- 0.024 Structural variation
- 0.024 MBD4
- 0.023 Lipoma
- More suggestions...