Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many Cancers. PTEN orthologs have been identified in most mammals for which complete genome data are available. (WikiPedia)
Tumor suppressor gene, PTEN encodes a lipid phosphatase that is an important negative regulator of PI3K-Akt signaling pathway
Table of Contents
Incoming Links #
Related Articles (Article 0) #
Related Medical Scholarly Articles (MedicalScholarlyArticle 1) #
- Comprehensive molecular portraits of human breast tumours
- Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Related Books (Book 2) #
Suggested Pages #
- 0.133 CDH1
- 0.115 Bone metastasis
- 0.076 Neoplasm
- 0.074 TP53
- 0.054 Imatinib
- 0.040 ABL1
- 0.032 DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression
- 0.032 Tyrosine-kinase inhibitor
- 0.030 Fusion gene
- 0.024 Oncogene
- More suggestions...