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Heparan sulfate #
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Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues. It occurs as a Proteoglycan (HSPG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins. It is in this form that HS binds to a variety of protein ligands and regulates a wide variety of biological activities, including developmental processes, Angiogenesis, Blood coagulation, abolishing detachment activity by GrB (Granzyme B), and tumour Metastasis.(

Heparin과 유사하지만 기본 구조가 약간 다르다.

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