Non-receptor tyrosine kinases (nRTKs) are cytoplasmic enzymes that are responsible for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, such as ATP, to a tyrosine residues in proteins. (http://en.wikipedia.org/wiki/Non-receptor_tyrosine_kinase)
Unlike the Receptor tyrosine kinases (RTKs), these are cytoplasmic enzymes.
다음과 같은 Oncogene 활성이 보고된 바 있다.
- BCR-ABL Gene fusion
- JAK2 point mutation activates JAK-STAT signaling pathway
Incoming Links #
Related Articles (Article 0) #
Suggested Pages #
- 0.301 Janus kinase inhibitor
- 0.173 Ruxolitinib
- 0.038 STAT
- 0.033 Alopecia areata
- 0.025 Acute lymphoblastic leukemia
- 0.025 BRAF
- 0.025 Tumor suppressor gene
- 0.024 Chromosomal translocation
- 0.024 ABL1
- 0.024 Hormone
- More suggestions...