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Apoptosis #
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Apoptosis is a process of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. (

Two pathways

  1. Intrinsic: 다양한 자극 --> DNA damage --> p53 response --> BCL2에 의해 mitochondrial 외부막의 투과성이 바뀌면서 cytochrome c가 흘러 나오면서 시작됨
  2. Extrinsic: CD95/Fas binds its ligand CD95L/FasL --> FADD

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