PLINK
#
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- (rev. 9)
- Hyungyong Kim
Structured data
- About
- GWAS
- Provider
- Broad Institute
- URL
- http://pngu.mgh.harvard.edu/~purcell/plink/index.shtml
PLINK is a free, Open source whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner. It's managed by Broad Institute.
The focus of PLINK is purely on analysis of genotype/phenotype data (GWAS). Through integration with gPLINK and Haploview, there is some support for the subsequent visualization, annotation and storage of results.
Data input
Table of Contents
주요 기능들 #
- Data management
- Basic statistics
- Linkage disequilibrium
- Distance matrices
- Identity-by-descent
- Population stratification
- Association analysis (GWAS)
- Family-based association
- Report postprocessing
- Epistasis
- Allelic scoring
Pairwise IBD estimation #
$ plink --genome full
모든 개체의 조합에 대해 IBD 추정함
IBS clustering #
$ plink --cluster
IBS로 군집분석 하고, 클러스터별 결과 제공
관련 정보 #
논문
- sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies bioRxiv
- BLINK: A Package for Next Level of Genome Wide Association Studies with Both Individuals and Markers in Millions bioRxiv : Big data 시대의 GWAS 도구로 PLINK와 비교하여 BLINK 프로그램 리뷰
Incoming Links #
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