KING: Kinship-based INference for Gwas

SNP array 데이터로 부터, 각 샘플들이 어떤 혈연관계인지 추정할 수 있다. 입력자료가 PLINK와 같다.

계산되는 Kinship coefficient와 P(IBD0)로 부터 추정할 수 있는 혈연관계는 다음과 같다.

(2nd degree: half-sib, avuncular pairs, grandparent-grandchild pairs; 3rd degree: first cousins)

참고자료

• Robust relationship inference in genome-wide association studies Bioinformatics 2010-10-05

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