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Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme Telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. (

Deregulation of telomerase expression in somatic cells may be involved in Oncogenesis. GWAS suggest TERT is a susceptibility gene for development of many cancers, including Lung cancer.

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