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A telomere is a region of repetitive nucleotide sequences at each end of a Chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. (https://en.wikipedia.org/wiki/Telomere)

Mitosis하면서 길이가 짧아진다. 그래서 노화과 관련있음.

Telomere-associated proteins

  • TRF1: 길이 유지 negatively regulated
  • TRF2: 말단 보호
  • POT1

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관련논문

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