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Sonic hedgehog is a protein that in humans is encoded by the SHH ("sonic hedgehog") gene. SHH is the best studied ligand of the Hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. (https://en.wikipedia.org/wiki/Sonic_hedgehog)
Cyclopamine에 의해 저해됨
참고정보
- 나무위키:소닉 헤지호그 단백질: 이름을 게임캐릭터 "소닉 더 헤지혹"에서 따왔다고
참고기사
- 뱀은 왜 다리가 없어졌을까? 양병찬 : 이 유전자 enhancer에서 3개 DNA의 결실을 발견함. 단백질 결합이 어려워지면서 아주 잠깐동안만 켜지고, 그래서 다리가 발생하지 않았다고.
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