Histone #
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Highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. (http://en.wikipedia.org/wiki/Histone)

Families
Structure
Histone code
Incoming Links
Suggested Pages

Families #

Linker

H1
- H1F: H1F0, H1FNT, H1FOO, H1FX
- H1H1: HIST1H1A, HIST1H1B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T

Core

H2A
- H2AF: H2AFB1, H2AFB2, H2AFB3, H2AFJ, H2AFV, H2AFX, H2AFY, H2AFY2, H2AFZ
- H2A1: HIST1H2AA, HIST1H2AB, HIST1H2AC, HIST1H2AD, HIST1H2AE, HIST1H2AG, HIST1H2AI, HIST1H2AJ, HIST1H2AK, HIST1H2AL, HIST1H2AM
- H2A2: HIST2H2AA3, HIST2H2AC
H2B
- H2BF: H2BFM, H2BFS, H2BFWT
- H2B1: HIST1H2BA, HIST1H2BB, HIST1H2BC, HIST1H2BD, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BH, HIST1H2BI, HIST1H2BJ, HIST1H2BK, HIST1H2BL, HIST1H2BM, HIST1H2BN, HIST1H2BO
- H2B2: HIST2H2BE
H3
- H3A1: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
- H3A2: HIST2H3C
- H3A3: HIST3H3
H4
- H41: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4G, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L
- H44: HIST4H4

Structure #

Histone code #

--> Histone modification에 의한 act/rep 코드

Incoming Links #

Related Datasets (Dataset 1) #

ENCODE

Related Books (Book 3) #

Epigenetics in Human Disease

Suggested Pages #

0.316 Synthetic lethality
0.067 Gene expression
0.067 Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
0.064 Polycomb-group proteins
0.050 WHSC1L1
0.050 DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression
0.037 KMT2A
0.033 Covalent modifications of histones during development and disease pathogenesis
0.033 Targeted genes by ChIP-seq
0.027 SMYD3
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