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Polycomb-group proteins #
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Polycomb-group (PcG) proteins are a family of proteins first discovered in fruit flies that can remodel Chromatin such that epigenetic silencing of genes takes place. (

PcG complexes

  1. RPC1 (maintain)
  2. RPC2 (initiation)


  1. PcG proteins silence some Tumor suppressor genes.
  2. PcG proteins regulate stem cells.
  3. PcG proteins and the links to signaling pathways

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