Polycomb-group (PcG) proteins are a family of proteins first discovered in fruit flies that can remodel Chromatin such that epigenetic silencing of genes takes place. (http://en.wikipedia.org/wiki/Polycomb-group_proteins)
PcG complexes
Functions
- PcG proteins silence some Tumor suppressor genes.
- PcG proteins regulate stem cells.
- PcG proteins and the links to signaling pathways
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