The cBioPortal for Cancer Genomics provides visualization, analysis and download of large-scale cancer genomics data sets.

TCGA 등 주요한 암 데이터를 분석하고 결과를 별도로 가시화 도구로 제공함. 자신의 데이터도 이곳에 등록시킬 수 있음.

It's developed and maintained by the Computational Biology Center at Memorial Sloan-Kettering Cancer Center and the i-Vis (Information Visualization) Research Group of the Computer Engineering Department at Bilkent University.

주요기능

• 특정 암 유전체 연구 혹은 전체 연구에 대해 유전자 목록을 입력하면, 다음 정보를 제공함
  1. OncoPrint: 유전자, 샘플별 변이현황
  2. Mutual Exclusivity: 유전자별 상호 관계
  3. Plots: 발현량 차트
  4. Mutation: 유전자 기준 세부 변이 현황
  5. Co-Expression: 발현 패턴 유사 유전자 확인
  6. Protein Changes
  7. Survival: Survival analysis
  8. Network: Biological network 분석
  9. IGV: Genome browser 연결
• Web API
• R Package

Funding

• The NCI as a TCGA Genome Data Analysis Center (GDAC)
• The NCRR as the National Resource for Network Biology (NRNB) Research Resource

관련 링크

• OncoPrinter
• CBioPortal.py Interface with cBioPortal with Python
• cBioPortal in 人CoDom

Incoming Links #

Related Medical Scholarly Articles (MedicalScholarlyArticle 0) #

• Genetic alterations of histone lysine methyltransferases and their significance in breast cancer

Related Datasets (Dataset 1) #

• CCLE
• GENIE

Related Articles (Article 2) #

• Histone methylation
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Related Education Events (EducationEvent 3) #

• 2015 통계유전학워크숍

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