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Oncotator #
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Structured data

Cancer genomics
Programming Language
Broad Institute

Oncotator is a web application for annotating human genomic point mutations and indels with data relevant to Cancer researchers. Annotations are aggregated from the following resources:

  1. Genomic Annotations
    • Gene, transcript, and functional consequence annotations using GENCODE for hg19.
    • Reference sequence around a variant.
    • GC content around a variant.
    • Human DNA Repair Gene annotations from Wood et al.
  2. Protein Annotations
    • Site-specific protein annotations from UniProt.
    • Functional impact predictions from dbNSFP.
  3. Cancer Variant Annotations
  4. Non-Cancer Variant Annotations
    • Common SNP annotations from dbSNP.
    • Variant annotations from 1000 Genomes Project.
    • Variant annotations from NHLBI GO Exome Sequencing Project (ESP).

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