SET and MYND domain-containing protein 3 (Smyd3, KMT3E) is a protein that in humans is encoded by the SMYD3 gene. SMYD3 is a Histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex. (https://en.wikipedia.org/wiki/SMYD3)
H3K4, H3K5를 메틸화하여 activator 역할