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Redirected from CD274
Programmed death-ligand 1 (PD-L1, PDL1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. (https://en.wikipedia.org/wiki/PD-L1)
Cancer 세포막에 발현되고 T cell 표면의 PD-1과 결합하여 면역 반응을 피한다. PD-L1 발현이 높은 암일 수록 예후가 좋지 않다. Nivolumab와 같은 약을 쓰면 PD-1에 결합하여 이 반응을 낮춘다.
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