The JAK-STAT signaling pathway transmits information from chemical signals outside the cell, through the cell membrane, and into gene promoters on the DNA in the cell nucleus, which causes DNA transcription and activity in the cell. (http://en.wikipedia.org/wiki/JAK-STAT_signaling_pathway)

The JAK-STAT system consists of three main components:

1. A receptor
2. Janus kinase (JAK)
3. Signal Transducer and Activator of Transcription (STAT)

Incoming Links #

Related Drug Classes (DrugClass 0) #

• Janus kinase inhibitor

Related Articles (Article 1) #

• JAK2
• Janus kinase
• Non-receptor tyrosine kinase

Suggested Pages #

• 0.452 Ruxolitinib
• 0.254 Alopecia areata
• 0.025 Angiogenesis
• 0.025 September 4
• 0.025 2019
• 0.024 Cytokine
• 0.012 BCR
• 0.012 Hyungyong Kim
• 0.012 Cell signaling
• 0.012 Fusion gene
• More suggestions...