Paclitaxel
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- (rev. 5)
- Hyungyong Kim
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- Drug Class
- Taxane
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Paclitaxel (PTX, 파클리탁셀), sold under the brand name Taxol (탁솔) among others, is a Chemotherapy medication used to treat a number of types of cancer. (https://en.wikipedia.org/wiki/Paclitaxel)
파클리탁셀은 주목나무로부터 만들어진다. Cell cycle 선택적으로 다양한 세포 분열 주기 중 다양한 단계의 암세포를 공격한다. Mitosis 과정 중 분열과 자가 복제의 기구인 미세소관(Microtubule)이 분리되는 과정을 방해함으로써 암세포의 증식을 억제한다.
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