NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. (NF-κB in Wikipedia)

NF-κB plays a key role in regulating the Immune system response to Infection (κ light chains are critical components of immunoglobulins).

Incorrect regulation of NF-κB has been linked to Cancer, inflammatory, and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory.

Incoming Links #

Related Medical Scholarly Articles (MedicalScholarlyArticle 0) #

• The landscape of somatic copy-number alteration across human cancers

Suggested Pages #

• 0.275 Copy-number variation
• 0.025 2017
• 0.025 Lymphoma
• 0.025 NewsPeppermint
• 0.025 April
• 0.025 2014
• 0.025 Liposarcoma
• 0.025 Secret Lab of a Mad Scientist
• 0.025 April 19
• 0.025 Cell
• More suggestions...