Hereditary nonpolyposis colorectal cancer
#
Find similar titles
- (rev. 4)
- Hyungyong Kim
Lynch syndrome (HNPCC) is an autosomal dominant genetic condition that has a high risk of Colon cancer as well as other cancers including endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair. (https://en.wikipedia.org/wiki/Hereditary_nonpolyposis_colorectal_cancer)
Microsatellite instability를 보임. MSH1, MSH2 유전자의 germline mutation에 의함
Suggested Pages #
- 0.546 Microsatellite instability in colorectal cancer
- 0.025 Exo1
- 0.025
- 0.025 RFP
- 0.025 MLH1
- 0.024 TCGA
- 0.024 Oncotarget
- 0.024 PCNA
- 0.023 February 4
- 0.023 Rectal cancer
- More suggestions...