Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. FLT3 is a Cytokine receptor which belongs to the RTK class III. CD135 is the receptor for the cytokine Flt3 ligand (FLT3L). (https://en.wikipedia.org/wiki/CD135)

FLT3의 변이가 Leukemia의 원인이 된다. 특히, AML.

METABRIC Survival analysis 자체 분석시 많이 발현될 수록 가장 오래사는 유전자였음. Proto-Oncogene의 하나라던데 의외네. --Hyungyong Kim, 2017-07-13

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