Aneuploidy (이수성) is the presence of an abnormal number of chromosomes (Ploidy) in a cell. (https://en.wikipedia.org/wiki/Aneuploidy)

다양한 유전병, Cancer와 연관되어 있다. 세포분열중 염색체가 정상적으로 분리되지 않아서이다.

Terminology

• Monosomy: 하나 부족 - Turner syndrome
• Disomy: 정상 (만일 3, 4개가 정상인 종에서는 비정상이겠죠)
• Trisomy: 3 카피
• Tetrasomy: 4 카피
• Pentasomy: 5 카피

관련 자료

• Genotype calling in tetraploid species from bi-allelic marker data using mixture models BMC Bioinformatics 2011-05-19
• A strategy for tetraploid genetic analysis using SNP markers

Incoming Links #

Related Medical Scholarly Articles (MedicalScholarlyArticle 0) #

• SAAS-CNV: A Joint Segmentation Approach on Aggregated and Allele Specific Signals for the Identification of Somatic Copy Number Alterations with Next-Generation Sequencing Data

Related Articles (Article 1) #

• Chromosome instability
• Genome instability
• Non-invasive prenatal test
• Ploidy
• Trisomy

Related Books (Book 2) #

• Epigenetics in Human Disease

Related Codes (Code 3) #

• ASCAT

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