Mitogen-activated protein kinase kinase kinase 1
MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including Insulin (MIM 176730) and many Growth factors. (http://en.wikipedia.org/wiki/MAP3K1)
Mouse genetics has revealed that the kinase is important in: correct Embryogenesis, keratinocyte migration, T cell cytokine production and B cell antibody production.
Incoming Links #
Related Medical Scholarly Articles (MedicalScholarlyArticle 0) #
- Comprehensive molecular portraits of human breast tumours
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Suggested Pages #
- 0.282 Breast cancer
- 0.025 Transforming growth factor alpha
- 0.025 FOXP3
- 0.025 Frederick Sanger
- 0.025 TGF-α
- 0.025 Vascular endothelial growth factor
- 0.025 EGF
- 0.025 B lymphocyte
- 0.025 Hormone
- 0.025 Fibroblast growth factor
- More suggestions...