Summary #

Approaches used for drug repurposing #

Computational approaches #

Signature matching #

Computational molecular docking #

Genome-wide association studies #

Pathway or network mapping #

Retrospective clinical analysis: use of electronic health records #

Novel sources of data for drug repurposing #

Experimental approaches #

Binding assays to identify target interactions #

Phenotypic screening #

Bariers to drug repurposing #

patent considerations #

Regulatory considerations #

Organizational hurdels in industry #

Collaborative models for drug repurposing #

Recommendations for drug repurposing #

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