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MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development #
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About
MEDICI
Date Published
Publisher
PLOS One
URL

Summary #

Introduction #

Methods #

Modeling PPI network topologies #

Calculate PPI essentialities and ranking #

Smoothing #

Data mining and statistical tests #

Results #

PPI essentiality ranking #

Clustering analysis #

Crosstalk of signal transduction pathways #

Drug sensitivity #

Genetic alterations #

Clinical outcome analysis #

Discussion #

Suggested Pages #

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