Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification
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Summary #
Introduction #
Materials and Methods #
Study Design and Clinical Samples #
WES and CNV analysis #
Tissue Microarray and Immunohistochemistry #
Quantitative Real-Time PCR #
Statistical Analysis #
Sequencing Data Deposition #
Results #
Clinical Features #
Significantly Mutated Genes and CNVs #
Pathways Altered in HCC #
Genetic Aberrations in HCC and Their Association With Postsurgical Outcomes #
Altered Expression Levels of RB and E2F1 Proteins in Tumors With RB1 Gene Inactivation #
Discussion #
Suggested Pages #
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MedicalScholarlyArticle