Genomic Selection in Aquaculture: Application, Limitations and Opportunities With Special Reference to Marine Shrimp and Pearl Oysters
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- (rev. 3)
- Hyungyong Kim
Structured data
- About
- Genomic selection
- Date Published
- Publisher
- Frontiers in Genetics
- URL
- https://www.frontiersin.org/articles/10.3389/fgene.2018.00693/full
수산분야에서 유전체 정보에 기반한 선발은 생산 기여에 중요하다. Genomic selection은 생물학적 경제형질과 연관된 genome-wide 마커에 대한 관계를 이용한다. 본 리뷰논문에서는 이의 기술적 향상, 실무적 필요사항, 상업적 응용에 대해 Pearl oysters와 Marine shrimp에 초점을 맞춰 살펴본다. 낮은 시퀀싱 가격으로 레퍼런스 없어도, 상용 칩 아니여도 저렴한 genotyping이 가능하다. Genotyping by sequencing 방식을 사용한다. 대규모 영상분석, 기계학습 방법으로 표현형 정보를 확보하고, Breeding value를 계산한다. 이 방법은 질병 저항성, increasing rates of genetic gain, 근친최소화 등 복잡한 polygenic traint을 예측한다. 또한 Genomic selection의 실무적 장점인 대규모 mating, rearing 시스템도 살펴본다.
Table of Contents
Summary #
Introduction #
General Principles of Genomic Selection #
Applications of Genomic Selection to Aquaculture #
Pathway for Incorporation of Genomic Selection into Aquaculture Breeding Programs #
Building Genomic Resources #
Optimizing Use of Genomic Resources #
Linking Genotype to Pheontype - Genes of Large Effect #
From MAS to Genomic Selection #
Accurate and Low-Cost Phenotyping #
Understanding Factors Affecting Utility of Genomic Selection #
Mating Design #
Number of Families #
Size of Families #
Number of Generations #
Application of Stagewise and Index Selection #
Exploiting Non-additive Genetic Variance #
Unequal Family Distribution and Maternal Effects #
Use of Realistic Species-Specific Linkage Disequilibrium #
Genotype by Environment Interaction #
Bio-economical Modeling #
Practical Considerations for Implementing Genomic Selection on Farm #
Future Outlook for Shrimp and Pearl Oyster Genomic Selection Application #
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