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G protein-coupled receptors (GPCR, G 단백질 연결 수용체), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses, Cell signaling. (https://en.wikipedia.org/wiki/G_protein-coupled_receptor)